Jury choice for the Elizabeth Holmes trial begins at this time.

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The jury selection begins Tuesday in the long-awaited trial of Elizabeth Holmes, the disgraced founder of blood testing startup Theranos, who has faced dozens of fraud and wire fraud conspiracies.

At the heart of the process are questions about what exactly Ms. Holmes, 37, knew about the problems with Theranos’ blood testing equipment and whether she deliberately misled investors about the company’s technology. If convicted, she faces up to 20 years imprisonment.

The case caught the public eye as another example of a Silicon Valley startup that went wrong. But Theranos was unusual in that it was run by a businesswoman. Mrs. Holmes used this difference to attract attention. She often wore a Steve Jobs-like uniform of a black turtleneck and spoke in an unusually deep voice. Before Theranos fell out of favor, Ms. Holmes was crowned the world’s youngest billionaire and regularly posed for magazine covers.

Your high profile can pose a challenge to the selection of the jury. Prosecutors and their defense lawyers may have difficulty selecting jurors who have not yet decided on the case. According to last week’s court records, around half of the 200 potential jurors had already consumed media related to the case.

Prospective jurors completed a 28-page questionnaire asking about their media consumption habits, medical history, and the knowledge of more than 200 potential witnesses. An even larger questionnaire prepared by Ms. Holmes’ legal team contained more than 100 questions. In June it was denied by Judge Edward Davila of the US District Court for the Northern District of California, who is overseeing the case. The trial is in San Jose, California.

The selection of the jury is expected to last until Wednesday and could take longer. The opening arguments begin next week.